A comprehensive platform for highly multiplexed mammalian functional genetic screens

BACKGROUND: Genome-wide screening in human and mouse cells using RNA interference and open reading frame over-expression libraries is rapidly becoming a viable experimental approach for many research labs. There are a variety of gene expression modulation libraries commercially available, however, d...

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Main Authors: Ketela, Troy, Heisler, Lawrence E, Brown, Kevin R, Ammar, Ron, Kasimer, Dahlia, Surendra, Anuradha, Ericson, Elke, Blakely, Kim, Karamboulas, Dina, Smith, Andrew M, Durbic, Tanja, Arnoldo, Anthony, Cheung-Ong, Kahlin, Koh, Judice LY, Gopal, Shuba, Cowley, Glenn S, Yang, Xiaoping, Grenier, Jennifer K, Giaever, Guri, Root, David E, Moffat, Jason, Nislow, Corey
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Methodology Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115879/
https://ncbi.nlm.nih.gov/pubmed/21548937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-213
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