Epigenetic Gene Promoter Methylation at Birth Is Associated With Child’s Later Adiposity

OBJECTIVE: Fixed genomic variation explains only a small proportion of the risk of adiposity. In animal models, maternal diet alters offspring body composition, accompanied by epigenetic changes in metabolic control genes. Little is known about whether such processes operate in humans. RESEARCH DESI...

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Detalhes bibliográficos
Main Authors: Godfrey, Keith M., Sheppard, Allan, Gluckman, Peter D., Lillycrop, Karen A., Burdge, Graham C., McLean, Cameron, Rodford, Joanne, Slater-Jefferies, Joanne L., Garratt, Emma, Crozier, Sarah R., Emerald, B. Starling, Gale, Catharine R., Inskip, Hazel M., Cooper, Cyrus, Hanson, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115550/
https://ncbi.nlm.nih.gov/pubmed/21471513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0979
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