A Novel Human IgA Monoclonal Antibody Protects against Tuberculosis

Abs have been shown to be protective in passive immunotherapy of tuberculous infection using mouse experimental models. In this study, we report on the properties of a novel human IgA1, constructed using a single-chain variable fragment clone (2E9), selected from an Ab phage library. The purified Ab...

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Detalhes bibliográficos
Main Authors: Balu, Sucharitha, Reljic, Rajko, Lewis, Melanie J., Pleass, Richard J., McIntosh, Richard, van Kooten, Cees, van Egmond, Marjolein, Challacombe, Stephen, Woof, Jenny M., Ivanyi, Juraj
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115510/
https://ncbi.nlm.nih.gov/pubmed/21257971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003189
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