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A Novel Human IgA Monoclonal Antibody Protects against Tuberculosis

Abs have been shown to be protective in passive immunotherapy of tuberculous infection using mouse experimental models. In this study, we report on the properties of a novel human IgA1, constructed using a single-chain variable fragment clone (2E9), selected from an Ab phage library. The purified Ab...

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Main Authors: Balu, Sucharitha, Reljic, Rajko, Lewis, Melanie J., Pleass, Richard J., McIntosh, Richard, van Kooten, Cees, van Egmond, Marjolein, Challacombe, Stephen, Woof, Jenny M., Ivanyi, Juraj
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115510/
https://ncbi.nlm.nih.gov/pubmed/21257971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003189
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