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Nonspecific DNA Binding and Bending by HU(αβ): Interfaces of the Three Binding Modes Characterized by Salt Dependent Thermodynamics
Previous ITC and FRET studies demonstrated that Escherichia coli HU(αβ) binds nonspecifically to duplex DNA in three different binding modes: a tighter-binding 34 bp mode which interacts with DNA in large (>34 bp) gaps between bound proteins, reversibly bending it 140° and thereby increasing its...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115508/ https://ncbi.nlm.nih.gov/pubmed/21513716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.001 |
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