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Nonspecific DNA Binding and Bending by HU(αβ): Interfaces of the Three Binding Modes Characterized by Salt Dependent Thermodynamics

Previous ITC and FRET studies demonstrated that Escherichia coli HU(αβ) binds nonspecifically to duplex DNA in three different binding modes: a tighter-binding 34 bp mode which interacts with DNA in large (>34 bp) gaps between bound proteins, reversibly bending it 140° and thereby increasing its...

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書誌詳細
主要な著者: Koh, Junseock, Shkel, Irina, Saecker, Ruth M., Record, M. Thomas
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115508/
https://ncbi.nlm.nih.gov/pubmed/21513716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.001
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