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Formation of A Wrapped DNA-Protein Interface: Expermental Characterization and Analysis of the Large Contributions of Ions and Water to the Thermodynamics of Binding IHF to H′DNA

To characterize driving forces and driven processes in formation of a large-interface, wrapped protein-DNA complex analogous to the nucleosome, we have investigated the thermodynamics of binding the 34 bp H′ DNA sequence to the E. coli DNA-remodeling protein Integration Host Factor (IHF). Isothermal...

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Main Authors: Vander Meulen, Kirk A., Saecker, Ruth M., Record, M. Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2336898/
https://ncbi.nlm.nih.gov/pubmed/18237740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.104
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