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Identification of Phenylalanine-3-Hydroxylase for meta-Tyrosine Biosynthesis

Phenylalanine hydroxylase (PheH) is a iron(II)-dependent enzyme that catalyzes the hydroxylation of aromatic amino acid l-phenylalanine (l-Phe) to l-tyrosine (l-Tyr). The enzymatic modification has been demonstrated to be highly regiospecific, forming proteinogenic para-Tyr (p-Tyr) exclusively. Here...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Wenjun, Ames, Brian D., Walsh, Christopher T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115494/
https://ncbi.nlm.nih.gov/pubmed/21615132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200733c
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