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HD Exchange and PLIMSTEX Determine the Affinities and Order of Binding of Ca(2+) with Troponin C

Troponin C (TnC), present in all striated muscle, is the Ca(2+)-activated trigger that initiates myocyte contraction. The binding of Ca(2+) to TnC initiates a cascade of conformational changes involving the constituent proteins of the thin filament. The functional properties of TnC and its ability t...

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Detalhes bibliográficos
Main Authors: Huang, Richard Y-C., Rempel, Don L., Gross, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115450/
https://ncbi.nlm.nih.gov/pubmed/21574565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200377c
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