Influence of enhanced troponin C Ca(2+)-binding affinity on cooperative thin filament activation in rabbit skeletal muscle

We studied how enhanced skeletal troponin C (sTnC) Ca(2+)-binding affinity affects cooperative thin filament activation and contraction in single demembranated rabbit psoas fibres. Three sTnC mutants were created and incorporated into skeletal troponin (sTn) for measurement of Ca(2+) dissociation, r...

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Detalhes bibliográficos
Main Authors: Kreutziger, Kareen L, Gillis, Todd E, Davis, Jonathan P, Tikunova, Svetlana B, Regnier, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Skeletal Muscle and Exercise
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277218/
https://ncbi.nlm.nih.gov/pubmed/17584846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.135426
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