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Cdc42 in oncogenic transformation, invasion, and tumorigenesis
The Rho family of GTPases represents a class of Ras-related signaling molecules often deregulated in cancer. Rho GTPases switch from a GDP-bound, inactive state to a GTP-bound, active state in response to extracellular stimuli such as mitogens and extracellular matrix. In addition, Rho GTPase signal...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115433/ https://ncbi.nlm.nih.gov/pubmed/21515363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.04.001 |
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