Mouse ES cells overexpressing DNMT1 produce abnormal neurons with upregulated NR1

High levels of DNA methyltransferase 1 (DNMT1), hypermethylation, and downregulation of GAD(67) and reelin have been described in GABAergic interneurons of patients with schizophrenia (SZ) and bipolar (BP) disorders. However, overexpression of DNMT1 is lethal, making it difficult to assess the direc...

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Detaylı Bibliyografya
Asıl Yazarlar: D'Aiuto, Leonardo, Di Maio, Roberto, Mohan, K. Naga, Minervini, Crescenzio, Saporiti, Federica, Soreca, Isabella, Greenamyre, J. Timothy, Chaillet, J. Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115397/
https://ncbi.nlm.nih.gov/pubmed/21492995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2011.03.003
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