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Mouse ES cells overexpressing DNMT1 produce abnormal neurons with upregulated NR1
High levels of DNA methyltransferase 1 (DNMT1), hypermethylation, and downregulation of GAD(67) and reelin have been described in GABAergic interneurons of patients with schizophrenia (SZ) and bipolar (BP) disorders. However, overexpression of DNMT1 is lethal, making it difficult to assess the direc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115397/ https://ncbi.nlm.nih.gov/pubmed/21492995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2011.03.003 |
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