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Dynamics of Cdk1 Substrate Specificity during the Cell Cycle

Cdk specificity is determined by the intrinsic selectivity of the active site and by substrate docking sites on the cyclin subunit. There is a long-standing debate about the relative importance of these factors in the timing of Cdk1 substrate phosphorylation. We analyzed major budding yeast cyclins...

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Autores principales: Kõivomägi, Mardo, Valk, Ervin, Venta, Rainis, Iofik, Anna, Lepiku, Martin, Morgan, David O., Loog, Mart
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115021/
https://ncbi.nlm.nih.gov/pubmed/21658602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.016
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