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A continuous-index Bayesian hidden Markov model for prediction of nucleosome positioning in genomic DNA

Nucleosomes are units of chromatin structure, consisting of DNA sequence wrapped around proteins called “histones.” Nucleosomes occur at variable intervals throughout genomic DNA and prevent transcription factor (TF) binding by blocking TF access to the DNA. A map of nucleosomal locations would enab...

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Autors principals: Mitra, Ritendranath, Gupta, Mayetri
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114652/
https://ncbi.nlm.nih.gov/pubmed/21193724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxq077
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