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Predicting nucleosome positioning using a duration Hidden Markov Model

BACKGROUND: The nucleosome is the fundamental packing unit of DNAs in eukaryotic cells. Its detailed positioning on the genome is closely related to chromosome functions. Increasing evidence has shown that genomic DNA sequence itself is highly predictive of nucleosome positioning genome-wide. Theref...

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Detalhes bibliográficos
Main Authors: Xi, Liqun, Fondufe-Mittendorf, Yvonne, Xia, Lei, Flatow, Jared, Widom, Jonathan, Wang, Ji-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900280/
https://ncbi.nlm.nih.gov/pubmed/20576140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-346
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