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A Bayesian hidden Markov model for motif discovery through joint modeling of genomic sequence and ChIP-chip data
We propose a unified framework for the analysis of Chromatin (Ch) Immunoprecipitation (IP) microarray (ChIP-chip) data for detecting transcription factor binding sites (TFBSs) or motifs. ChIP-chip assays are used to focus the genome-wide search for TFBSs by isolating a sample of DNA fragments with T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794970/ https://ncbi.nlm.nih.gov/pubmed/19210737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2008.01180.x |
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