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IL-15 ex vivo overcomes CD4(+) T cell deficiency for the induction of human antigen-specific CD8(+) T cell responses
CD4(+) Th cells are important for the induction and maintenance of antigen-specific CD8(+) T cell function, so their loss or dysfunction in HIV-infected or cancer patients could reduce the patients' ability to control viral infection. Previous work in murine systems indicated that IL-15 codeliv...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Leukocyte Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114597/ https://ncbi.nlm.nih.gov/pubmed/21474552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1010579 |
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