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Transcriptional regulation of the major HIV-1 coreceptor, CXCR4, by the κ opioid receptor
Previous studies have demonstrated that KOR activation results in decreased susceptibility to infection by HIV-1 in human PBMCs. In the present studies, we have found this effect is, in part, a result of down-regulation of the major HIV-1 coreceptor, CXCR4. Using a combination of biochemical approac...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114596/ https://ncbi.nlm.nih.gov/pubmed/21447649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1010546 |
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