OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to the salivary gland, and exit the arthropod vector. Here we show that OspC strongly binds to th...

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Detalhes bibliográficos
Main Authors: Pal, Utpal, Yang, Xiaofeng, Chen, Manchuan, Bockenstedt, Linda K., Anderson, John F., Flavell, Richard A., Norgard, Michael V., Fikrig, Erol
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC311436/
https://ncbi.nlm.nih.gov/pubmed/14722614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419894
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