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OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to the salivary gland, and exit the arthropod vector. Here we show that OspC strongly binds to th...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Pal, Utpal, Yang, Xiaofeng, Chen, Manchuan, Bockenstedt, Linda K., Anderson, John F., Flavell, Richard A., Norgard, Michael V., Fikrig, Erol
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14722614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19894
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