OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to the salivary gland, and exit the arthropod vector. Here we show that OspC strongly binds to th...

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Bibliografiska uppgifter
Huvudupphovsmän: Pal, Utpal, Yang, Xiaofeng, Chen, Manchuan, Bockenstedt, Linda K., Anderson, John F., Flavell, Richard A., Norgard, Michael V., Fikrig, Erol
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2004
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC311436/
https://ncbi.nlm.nih.gov/pubmed/14722614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419894
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