OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to the salivary gland, and exit the arthropod vector. Here we show that OspC strongly binds to th...

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Main Authors: Pal, Utpal, Yang, Xiaofeng, Chen, Manchuan, Bockenstedt, Linda K., Anderson, John F., Flavell, Richard A., Norgard, Michael V., Fikrig, Erol
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2004
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC311436/
https://ncbi.nlm.nih.gov/pubmed/14722614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419894
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