Immunogenicity of a meningococcal native outer membrane vesicle vaccine with attenuated endotoxin and over-expressed factor H binding protein in infant rhesus monkeys

We previously investigated immunogenicity of meningococcal native outer membrane vesicle (NOMV) vaccines prepared from recombinant strains with attenuated endotoxin (ΔLpxL1) and over-expressed factor H binding protein (fHbp) in a mouse model. The vaccines elicited broad serum bactericidal antibody r...

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Bibliografiska uppgifter
Huvudupphovsmän: Koeberling, Oliver, Seubert, Anja, Santos, George, Colaprico, Annalisa, Ugozzoli, Mildred, Donnelly, John, Granoff, Dan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114263/
https://ncbi.nlm.nih.gov/pubmed/21571025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.04.095
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