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CHFR binds to and regulates MAD2 in the spindle checkpoint through its cysteine-rich domain
CHFR has been implicated as a tumor suppressor in a multitude of cancers. It was originally identified as a major component of the antephase checkpoint. Recently, CHFR was reported to interact with MAD2, an important component of the spindle assembly checkpoint, where CHFR knockdown resulted in misl...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114255/ https://ncbi.nlm.nih.gov/pubmed/21575600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.04.143 |
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