Trimodal Glioblastoma Treatment Consisting of Concurrent Radiotherapy, Temozolomide, and the Novel TGF-β Receptor I Kinase Inhibitor LY2109761

Here we investigate the effects of the novel transforming growth factor-β receptor I (TGF-βRI) serine/threonine kinase inhibitor LY2109761 on glioblastoma when combined with the present clinical standard combination regimen radiotherapy and temozolomide (TMZ). Human GBM U87 (methylated MGMT promoter...

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Autores principales: Zhang, Mengxian, Herion, Tobias W, Timke, Carmen, Han, Na, Hauser, Kai, Weber, Klaus J, Peschke, Peter, Wirkner, Ute, Lahn, Michael, Huber, Peter E
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114247/
https://ncbi.nlm.nih.gov/pubmed/21677877
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