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Translating the combination of TGFβ blockade and radiotherapy into clinical development in glioblastoma

To improve multimodal glioblastoma treatment strategies, it appears useful to integrate a selective inhibitor of the TβR-I kinase, which may be able to potentiate radiation responses by increasing apoptosis and cancer-stem-like cell targeting while blocking DNA damage repair, invasion, mesenchymal t...

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Detalhes bibliográficos
Main Authors: Zhang, Mengxian, Lahn, Michael, Huber, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489753/
https://ncbi.nlm.nih.gov/pubmed/23162765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19789
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