TGF-β receptor inhibitor LY2109761 enhances the radiosensitivity of gastric cancer by inactivating the TGF-β/SMAD4 signaling pathway

Radiotherapy is used to treat gastric cancer (GC); however, radioresistance challenges the clinical outcomes of GC, and the mechanisms of radioresistance in GC remain poorly understood. Here, we report that the TGF-β receptor inhibitor, LY2109761 (LY), is a potential radiosensitizer both in vitro an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging (Albany NY)
Egile Nagusiak: Yang, Tian, Huang, Tianhe, Zhang, Dongdong, Wang, Miao, Wu, Balu, Shang, Yufeng, Sattar, Safat, Ding, Lu, Liu, Yin, Jiang, Hongqiang, Liang, Yuxing, Zhou, Fuling, Wei, Yongchang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834415/
https://ncbi.nlm.nih.gov/pubmed/31631064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102329
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