Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type β signaling

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by endocrine tumors of parathyroids, pancreatic islets, and anterior pituitary. The MEN1 gene encodes a nuclear protein called menin. In MEN1 carriers inactivating mutations give rise to a truncated product co...

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Detaylı Bibliyografya
Asıl Yazarlar: Kaji, Hiroshi, Canaff, Lucie, Lebrun, Jean-Jacques, Goltzman, David, Hendy, Geoffrey N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2001
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC31139/
https://ncbi.nlm.nih.gov/pubmed/11274402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061358098
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