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Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type β signaling
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by endocrine tumors of parathyroids, pancreatic islets, and anterior pituitary. The MEN1 gene encodes a nuclear protein called menin. In MEN1 carriers inactivating mutations give rise to a truncated product co...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
The National Academy of Sciences
2001
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31139/ https://ncbi.nlm.nih.gov/pubmed/11274402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061358098 |
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