Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type β signaling

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by endocrine tumors of parathyroids, pancreatic islets, and anterior pituitary. The MEN1 gene encodes a nuclear protein called menin. In MEN1 carriers inactivating mutations give rise to a truncated product co...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Proc Natl Acad Sci U S A
Huvudupphov:	Kaji, Hiroshi, Canaff, Lucie, Lebrun, Jean-Jacques, Goltzman, David, Hendy, Geoffrey N.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	National Academy of Sciences 2001
Ämnen:	Biological Sciences
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31139/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061358098
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!