A carregar...

Nitric Oxide Modulates TGF-β–Directive Signals To Suppress Foxp3(+) Regulatory T Cell Differentiation and Potentiate Th1 Development

TGF-β can induce Foxp3(+) inducible regulatory T cells (Treg) and also synergize with IL-6 and IL-4 to induce Th17 and Th9 cells. We now report that NO modulates TGF-β activity away from Treg but toward the Th1 lineage. NO potentiated Th1 differentiation in the presence of TGF-β in both IL-12–indepe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lee, Seung-Woo, Choi, Heonsik, Eun, So-Young, Fukuyama, Satoshi, Croft, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113707/
https://ncbi.nlm.nih.gov/pubmed/21555530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100485
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!