Nitric Oxide-induced regulatory T cells inhibit Th17 but not Th1 cell differentiation and function

Nitric oxide (NO) is a free radical with pleiotropic functions. We have shown earlier that NO induces a population of CD4(+)CD25(+)Foxp3(−) regulatory T cells (NO-Tregs) which suppress the functions of CD4(+)CD25(−) effector T cells in vitro and in vivo. We report here an unexpected finding that NO-...

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Detalhes bibliográficos
Main Authors: Niedbala, Wanda, Besnard, Anne-Gaelle, Jiang, Hui R, Alves-Filho, Jose C, Fukada, Sandra Y, Nascimento, Daniela, Mitani, Akio, Pushparaj, Peter, Alqahtani, Mohammed H, Liew, Foo Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785138/
https://ncbi.nlm.nih.gov/pubmed/23720815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202580
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