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The cap-binding translation initiation factor, eIF4E, binds a pseudoknot in a viral cap-independent translation element
Eukaryotic initiation factor eIF4E performs a key early step in translation by specifically recognizing the m(7)GpppN cap structure at the 5' end of cellular mRNAs. Many viral mRNAs lack a 5' cap and thus bypass eIF4E. In contrast, we reported a novel cap-independent translation element (P...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113551/ https://ncbi.nlm.nih.gov/pubmed/21645857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.03.013 |
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