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Polymerases in Nonhomologous End Joining: Building a Bridge over Broken Chromosomes
Repair of double-strand breaks in chromosomal DNA is essential. Unfortunately, a paradigm central to most DNA repair pathways—damaged DNA is replaced by polymerases, by using an intact, undamaged complementary strand as a template—no longer works. The nonhomologous end joining (NHEJ) pathway neverth...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mary Ann Liebert, Inc.
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113452/ https://ncbi.nlm.nih.gov/pubmed/20649463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3429 |
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