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Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis
Urinary tract morphogenesis requires subdivision of the ureteric bud (UB) into the intra-renal collecting system and the extra-renal ureter, by responding to signals in its surrounding mesenchyme. BMP4 is a mesenchymal regulator promoting ureter development, while GREM1 is necessary to negatively re...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113441/ https://ncbi.nlm.nih.gov/pubmed/21281623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.01.027 |
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