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Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis

Urinary tract morphogenesis requires subdivision of the ureteric bud (UB) into the intra-renal collecting system and the extra-renal ureter, by responding to signals in its surrounding mesenchyme. BMP4 is a mesenchymal regulator promoting ureter development, while GREM1 is necessary to negatively re...

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Detalhes bibliográficos
Main Authors: Nie, Xuguang, Xu, Jinshu, El-Hashash, Ahmed, Xu, Pin-Xian
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113441/
https://ncbi.nlm.nih.gov/pubmed/21281623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.01.027
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