Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis

Accumulation of misfolded neurotoxic Cu, Zn-superoxide dismutase-1 (SOD1) protein found in both familial and sporadic amyotrophic lateral sclerosis (ALS) is recognized as an important contributing factor of neuronal cell death. However, little is known about the mechanisms controlling the accumulati...

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Autors principals: Ren, Guijie, Ma, Zhongcai, Hui, Maria, Kudo, Lili C, Hui, Koon-Sea, Karsten, Stanislav L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113298/
https://ncbi.nlm.nih.gov/pubmed/21548977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-29
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