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Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators

Selective estrogen receptor modulators, such as estradiol 17α-derived metal complexes, have been synthesized as targeted probes for the diagnosis and treatment of breast cancer. Here, we report the detailed 3D structure of estrogen receptor alpha ligand-binding domain (ERα-LBD) bound with a novel es...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Min-Jun, Greenblatt, Harry M, Dym, Orly, Albeck, Shira, Pais, Adi, Gunanathan, Chidambaram, Milstein, David, Degani, Hadassa, Sussman, Joel L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112352/
https://ncbi.nlm.nih.gov/pubmed/21473635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200192y
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