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Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function
Antizyme inhibitor (AzI) regulates cellular polyamine homeostasis by binding to the polyamine-induced protein, Antizyme (Az), with greater affinity than ornithine decarboxylase (ODC). AzI is highly homologous to ODC but is not enzymatically active. In order to understand these specific characteristi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327289/ https://ncbi.nlm.nih.gov/pubmed/18369191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073427208 |
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