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8-Chloro-Cyclic AMP and Protein Kinase A I-Selective Cyclic AMP Analogs Inhibit Cancer Cell Growth through Different Mechanisms

Cyclic AMP (cAMP) inhibits the proliferation of several tumor cells. We previously reported an antiproliferative effect of PKA I-selective cAMP analogs (8-PIP-cAMP and 8-HA-cAMP) on two human cancer cell lines of different origin. 8-Cl-cAMP, another cAMP analog with known antiproliferative propertie...

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Библиографические подробности
Главные авторы: Lucchi, Simona, Calebiro, Davide, de Filippis, Tiziana, Grassi, Elisa S., Borghi, Maria Orietta, Persani, Luca
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112188/
https://ncbi.nlm.nih.gov/pubmed/21695205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020785
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