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Dengue Virus Tropism in Humanized Mice Recapitulates Human Dengue Fever

Animal models of dengue virus disease have been very difficult to develop because of the virus' specificity for infection and replication in certain human cells. We developed a model of dengue fever in immunodeficient mice transplanted with human stem cells from umbilical cord blood. These mice...

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Détails bibliographiques
Auteurs principaux: Mota, Javier, Rico-Hesse, Rebeca
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112147/
https://ncbi.nlm.nih.gov/pubmed/21695193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020762
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