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Humanized Mice Show Clinical Signs of Dengue Fever according to Infecting Virus Genotype

We demonstrated that the infection of humanized NOD-scid IL2rγ (null) mice with different strains (representing the four genotypes) of dengue virus serotype 2 (DEN-2) can induce the development of human-like disease, including fever, viremia, erythema, and thrombocytopenia. Newborn mice were irradia...

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Bibliografische gegevens
Hoofdauteurs: Mota, Javier, Rico-Hesse, Rebeca
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738212/
https://ncbi.nlm.nih.gov/pubmed/19535452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00581-09
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