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Humanized Mice Show Clinical Signs of Dengue Fever according to Infecting Virus Genotype
We demonstrated that the infection of humanized NOD-scid IL2rγ (null) mice with different strains (representing the four genotypes) of dengue virus serotype 2 (DEN-2) can induce the development of human-like disease, including fever, viremia, erythema, and thrombocytopenia. Newborn mice were irradia...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738212/ https://ncbi.nlm.nih.gov/pubmed/19535452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00581-09 |
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