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Dengue Virus Tropism in Humanized Mice Recapitulates Human Dengue Fever

Animal models of dengue virus disease have been very difficult to develop because of the virus' specificity for infection and replication in certain human cells. We developed a model of dengue fever in immunodeficient mice transplanted with human stem cells from umbilical cord blood. These mice...

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Autors principals: Mota, Javier, Rico-Hesse, Rebeca
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112147/
https://ncbi.nlm.nih.gov/pubmed/21695193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020762
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