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Dengue Virus Tropism in Humanized Mice Recapitulates Human Dengue Fever

Animal models of dengue virus disease have been very difficult to develop because of the virus' specificity for infection and replication in certain human cells. We developed a model of dengue fever in immunodeficient mice transplanted with human stem cells from umbilical cord blood. These mice...

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Hlavní autoři: Mota, Javier, Rico-Hesse, Rebeca
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112147/
https://ncbi.nlm.nih.gov/pubmed/21695193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020762
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