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Clarifying mammalian RISC assembly in vitro
BACKGROUND: Argonaute, the core component of the RNA induced silencing complex (RISC), binds to mature miRNAs and regulates gene expression at transcriptional or post-transcriptional level. We recently reported that Argonaute 2 (Ago2) also assembles into complexes with miRNA precursors (pre-miRNAs)....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3112105/ https://ncbi.nlm.nih.gov/pubmed/21529364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-12-19 |
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