A novel site of antibiotic action in the ribosome: Interaction of evernimicin with the large ribosomal subunit

Evernimicin (Evn), an oligosaccharide antibiotic, interacts with the large ribosomal subunit and inhibits bacterial protein synthesis. RNA probing demonstrated that the drug protects a specific set of nucleotides in the loops of hairpins 89 and 91 of 23S rRNA in bacterial and archaeal ribosomes. Spo...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Belova, Larissa, Tenson, Tanel, Xiong, Liqun, McNicholas, Paul M., Mankin, Alexander S.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 2001
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31120/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071527498
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