A novel site of antibiotic action in the ribosome: Interaction of evernimicin with the large ribosomal subunit
Evernimicin (Evn), an oligosaccharide antibiotic, interacts with the large ribosomal subunit and inhibits bacterial protein synthesis. RNA probing demonstrated that the drug protects a specific set of nucleotides in the loops of hairpins 89 and 91 of 23S rRNA in bacterial and archaeal ribosomes. Spo...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31120/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071527498 |
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