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Chromosome Damage and Repair in Children with Sickle Cell Anaemia and Long-Term Hydroxycarbamide Exposure

Hydroxycarbamide (hydroxyurea) provides laboratory and clinical benefits for adults and children with sickle cell anaemia (SCA). Given its mechanism of action and prior reports of genotoxicity, concern exists regarding long-term toxicities and possible carcinogenicity. We performed cross-sectional a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: McGann, Patrick T., Howard, Thad A., Flanagan, Jonathan M., Lahti, Jill M., Ware, Russell E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111895/
https://ncbi.nlm.nih.gov/pubmed/21542824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08698.x
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