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Chromosome Damage and Repair in Children with Sickle Cell Anaemia and Long-Term Hydroxycarbamide Exposure

Hydroxycarbamide (hydroxyurea) provides laboratory and clinical benefits for adults and children with sickle cell anaemia (SCA). Given its mechanism of action and prior reports of genotoxicity, concern exists regarding long-term toxicities and possible carcinogenicity. We performed cross-sectional a...

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Hlavní autoři: McGann, Patrick T., Howard, Thad A., Flanagan, Jonathan M., Lahti, Jill M., Ware, Russell E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111895/
https://ncbi.nlm.nih.gov/pubmed/21542824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08698.x
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