Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

Emerging evidence indicates that NADPH oxidase (NOX) and its reactive oxygen species (ROS) products modulate a variety of cellular events, including proliferation, differentiation, and apoptosis. In this study, we investigated the functions of NOX2 and ROS in immune modulation using NOX2 knockout (K...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Kihyun, Won, Hee Yeon, Bae, Myung Ae, Hong, Jeong-Ho, Hwang, Eun Sook
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111328/
https://ncbi.nlm.nih.gov/pubmed/21593419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012645108
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