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Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
Protection of the endothelium is provided by circulating sphingosine-1-phosphate (S1P), which maintains vascular integrity. We show that HDL-associated S1P is bound specifically to both human and murine apolipoprotein M (apoM). Thus, isolated human ApoM(+) HDL contained S1P, whereas ApoM(−) HDL did...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111292/ https://ncbi.nlm.nih.gov/pubmed/21606363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103187108 |
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