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Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity

Amyloid fiber formation is correlated with pathology in many diseases, including Alzheimer’s, Parkinson’s, and type II diabetes. Although β-sheet–rich fibrillar protein deposits define this class of disorder, increasing evidence points toward small oligomeric species as being responsible for cell dy...

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Podrobná bibliografie
Hlavní autoři: Last, Nicholas B., Rhoades, Elizabeth, Miranker, Andrew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111278/
https://ncbi.nlm.nih.gov/pubmed/21606325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102356108
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